Clinical Orthopaedics and Related Research ®

A Publication of The Association of Bone and Joint Surgeons ®

Symposium: Recent Advancements in amputation surgery and rehabilitation 1 article


Targeted Muscle Reinnervation: A Novel Approach to Postamputation Neuroma Pain

Jason M. Souza MD, Jennifer E. Cheesborough MD, Jason H. Ko MD, Mickey S. Cho MD, Todd A. Kuiken MD, PhD, Gregory A. Dumanian MD

Postamputation neuroma pain can prevent comfortable prosthesis wear in patients with limb amputations, and currently available treatments are not consistently effective. Targeted muscle reinnervation (TMR) is a decade-old technique that employs a series of novel nerve transfers to permit intuitive control of upper-limb prostheses. Clinical experience suggests that it may also serve as an effective therapy for postamputation neuroma pain; however, this has not been explicitly studied.